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rabbit polyclonal anti asic2a  (Alomone Labs)


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    Alomone Labs rabbit polyclonal anti asic2a
    Rabbit Polyclonal Anti Asic2a, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 31 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit polyclonal anti asic2a/product/Alomone Labs
    Average 93 stars, based on 31 article reviews
    rabbit polyclonal anti asic2a - by Bioz Stars, 2026-03
    93/100 stars

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    Alomone Labs polyclonal asic2 antibody
    Expression of asic1, <t>asic2</t> and asic3 during ALS disease progression. (a) Co-staining of lumbar spinal cords from tg SOD1- and asic1a-deficient mice with anti-ASIC1/ASIC2 (red) and anti-NeuN/GFAP (green) antibodies. Arrowheads show co-localization of ASIC1 and ASIC2 with NeuN on cell soma of neurons with motoneuron morphology. Scale bar=20 μm. (b) asic1, −2 and −3 mRNA expression in the transgenic (tg) SOD1 mouse; lumbar spinal cord lysates show a significant upregulation of the asic1a and asic2a mRNA; *P<0.01. Data displayed as mean±S.D.; n=6/group. (c) Co-staining of lumbar spinal cords across disease progression in the tg SOD1 mouse with anti-ASIC1/ASIC2 (red) and anti-NeuN/smi-32 (green) antibodies. Co-localization of ASIC antibodies with motoneurons is indicated by arrowheads. Scale bar=15 μm. (d) An increase in ASIC1 and ASIC2 protein levels in the tg SOD1 mouse; *P<0.01. Data displayed as mean±S.D.; n=6/group. (e) A representative image of ASIC1 and ASIC2 protein (double band) levels by western blotting, n=3 experiments with tubulin as loading control. (f) ASIC2 immunohistochemistry in ventral motoneurons of lumbar spinal cord sections from ALS and non-ALS patients. n=3/group. Scale bar=50 μm
    Polyclonal Asic2 Antibody, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Expression of asic1, <t>asic2</t> and asic3 during ALS disease progression. (a) Co-staining of lumbar spinal cords from tg SOD1- and asic1a-deficient mice with anti-ASIC1/ASIC2 (red) and anti-NeuN/GFAP (green) antibodies. Arrowheads show co-localization of ASIC1 and ASIC2 with NeuN on cell soma of neurons with motoneuron morphology. Scale bar=20 μm. (b) asic1, −2 and −3 mRNA expression in the transgenic (tg) SOD1 mouse; lumbar spinal cord lysates show a significant upregulation of the asic1a and asic2a mRNA; *P<0.01. Data displayed as mean±S.D.; n=6/group. (c) Co-staining of lumbar spinal cords across disease progression in the tg SOD1 mouse with anti-ASIC1/ASIC2 (red) and anti-NeuN/smi-32 (green) antibodies. Co-localization of ASIC antibodies with motoneurons is indicated by arrowheads. Scale bar=15 μm. (d) An increase in ASIC1 and ASIC2 protein levels in the tg SOD1 mouse; *P<0.01. Data displayed as mean±S.D.; n=6/group. (e) A representative image of ASIC1 and ASIC2 protein (double band) levels by western blotting, n=3 experiments with tubulin as loading control. (f) ASIC2 immunohistochemistry in ventral motoneurons of lumbar spinal cord sections from ALS and non-ALS patients. n=3/group. Scale bar=50 μm
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    Expression of asic1, <t>asic2</t> and asic3 during ALS disease progression. (a) Co-staining of lumbar spinal cords from tg SOD1- and asic1a-deficient mice with anti-ASIC1/ASIC2 (red) and anti-NeuN/GFAP (green) antibodies. Arrowheads show co-localization of ASIC1 and ASIC2 with NeuN on cell soma of neurons with motoneuron morphology. Scale bar=20 μm. (b) asic1, −2 and −3 mRNA expression in the transgenic (tg) SOD1 mouse; lumbar spinal cord lysates show a significant upregulation of the asic1a and asic2a mRNA; *P<0.01. Data displayed as mean±S.D.; n=6/group. (c) Co-staining of lumbar spinal cords across disease progression in the tg SOD1 mouse with anti-ASIC1/ASIC2 (red) and anti-NeuN/smi-32 (green) antibodies. Co-localization of ASIC antibodies with motoneurons is indicated by arrowheads. Scale bar=15 μm. (d) An increase in ASIC1 and ASIC2 protein levels in the tg SOD1 mouse; *P<0.01. Data displayed as mean±S.D.; n=6/group. (e) A representative image of ASIC1 and ASIC2 protein (double band) levels by western blotting, n=3 experiments with tubulin as loading control. (f) ASIC2 immunohistochemistry in ventral motoneurons of lumbar spinal cord sections from ALS and non-ALS patients. n=3/group. Scale bar=50 μm
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    Alpha Diagnostics primary affinity-purified rabbit polyclonal antibody against asic1a, asic2a, and asic2b
    Expression of asic1, <t>asic2</t> and asic3 during ALS disease progression. (a) Co-staining of lumbar spinal cords from tg SOD1- and asic1a-deficient mice with anti-ASIC1/ASIC2 (red) and anti-NeuN/GFAP (green) antibodies. Arrowheads show co-localization of ASIC1 and ASIC2 with NeuN on cell soma of neurons with motoneuron morphology. Scale bar=20 μm. (b) asic1, −2 and −3 mRNA expression in the transgenic (tg) SOD1 mouse; lumbar spinal cord lysates show a significant upregulation of the asic1a and asic2a mRNA; *P<0.01. Data displayed as mean±S.D.; n=6/group. (c) Co-staining of lumbar spinal cords across disease progression in the tg SOD1 mouse with anti-ASIC1/ASIC2 (red) and anti-NeuN/smi-32 (green) antibodies. Co-localization of ASIC antibodies with motoneurons is indicated by arrowheads. Scale bar=15 μm. (d) An increase in ASIC1 and ASIC2 protein levels in the tg SOD1 mouse; *P<0.01. Data displayed as mean±S.D.; n=6/group. (e) A representative image of ASIC1 and ASIC2 protein (double band) levels by western blotting, n=3 experiments with tubulin as loading control. (f) ASIC2 immunohistochemistry in ventral motoneurons of lumbar spinal cord sections from ALS and non-ALS patients. n=3/group. Scale bar=50 μm
    Primary Affinity Purified Rabbit Polyclonal Antibody Against Asic1a, Asic2a, And Asic2b, supplied by Alpha Diagnostics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Expression of asic1, asic2 and asic3 during ALS disease progression. (a) Co-staining of lumbar spinal cords from tg SOD1- and asic1a-deficient mice with anti-ASIC1/ASIC2 (red) and anti-NeuN/GFAP (green) antibodies. Arrowheads show co-localization of ASIC1 and ASIC2 with NeuN on cell soma of neurons with motoneuron morphology. Scale bar=20 μm. (b) asic1, −2 and −3 mRNA expression in the transgenic (tg) SOD1 mouse; lumbar spinal cord lysates show a significant upregulation of the asic1a and asic2a mRNA; *P<0.01. Data displayed as mean±S.D.; n=6/group. (c) Co-staining of lumbar spinal cords across disease progression in the tg SOD1 mouse with anti-ASIC1/ASIC2 (red) and anti-NeuN/smi-32 (green) antibodies. Co-localization of ASIC antibodies with motoneurons is indicated by arrowheads. Scale bar=15 μm. (d) An increase in ASIC1 and ASIC2 protein levels in the tg SOD1 mouse; *P<0.01. Data displayed as mean±S.D.; n=6/group. (e) A representative image of ASIC1 and ASIC2 protein (double band) levels by western blotting, n=3 experiments with tubulin as loading control. (f) ASIC2 immunohistochemistry in ventral motoneurons of lumbar spinal cord sections from ALS and non-ALS patients. n=3/group. Scale bar=50 μm

    Journal: Cell Death and Differentiation

    Article Title: Acidotoxicity and acid-sensing ion channels contribute to motoneuron degeneration

    doi: 10.1038/cdd.2012.158

    Figure Lengend Snippet: Expression of asic1, asic2 and asic3 during ALS disease progression. (a) Co-staining of lumbar spinal cords from tg SOD1- and asic1a-deficient mice with anti-ASIC1/ASIC2 (red) and anti-NeuN/GFAP (green) antibodies. Arrowheads show co-localization of ASIC1 and ASIC2 with NeuN on cell soma of neurons with motoneuron morphology. Scale bar=20 μm. (b) asic1, −2 and −3 mRNA expression in the transgenic (tg) SOD1 mouse; lumbar spinal cord lysates show a significant upregulation of the asic1a and asic2a mRNA; *P<0.01. Data displayed as mean±S.D.; n=6/group. (c) Co-staining of lumbar spinal cords across disease progression in the tg SOD1 mouse with anti-ASIC1/ASIC2 (red) and anti-NeuN/smi-32 (green) antibodies. Co-localization of ASIC antibodies with motoneurons is indicated by arrowheads. Scale bar=15 μm. (d) An increase in ASIC1 and ASIC2 protein levels in the tg SOD1 mouse; *P<0.01. Data displayed as mean±S.D.; n=6/group. (e) A representative image of ASIC1 and ASIC2 protein (double band) levels by western blotting, n=3 experiments with tubulin as loading control. (f) ASIC2 immunohistochemistry in ventral motoneurons of lumbar spinal cord sections from ALS and non-ALS patients. n=3/group. Scale bar=50 μm

    Article Snippet: Sections were incubated with a polyclonal ASIC2 antibody (1 : 200, Alomone Labs, Jerusalem, Israel), biotinylated secondary antibody (1 : 500; Jackson Laboratories) and visualized using Sigma fast 3,3-diaminobenzadine tablets.

    Techniques: Expressing, Staining, Transgenic Assay, Western Blot, Immunohistochemistry

    (A) Characteristics of cases and controls used from ALS and non-ALS patients. (B) Mean staining intensity values for  ASIC2  protein in ALS and non-ALS patients

    Journal: Cell Death and Differentiation

    Article Title: Acidotoxicity and acid-sensing ion channels contribute to motoneuron degeneration

    doi: 10.1038/cdd.2012.158

    Figure Lengend Snippet: (A) Characteristics of cases and controls used from ALS and non-ALS patients. (B) Mean staining intensity values for ASIC2 protein in ALS and non-ALS patients

    Article Snippet: Sections were incubated with a polyclonal ASIC2 antibody (1 : 200, Alomone Labs, Jerusalem, Israel), biotinylated secondary antibody (1 : 500; Jackson Laboratories) and visualized using Sigma fast 3,3-diaminobenzadine tablets.

    Techniques: Staining